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Word   Automated Fecal Occult Blood Test
Submit a single random sample from one stool specimen collected in FOBT Sample Collection Device. (stool specimen should coat the ridges of the probe in sample bottle)
Word   Prothrombin Gene Mutation (also known as Factor II)
Effective January 1, 2005, the volume of whole blood necessary for the performance of Prothrombin Gene Mutation testing is reduced to a minimum of 0.5 mL of whole blood in an EDTA tube. Volumes less than 0.5 mL may lead to failed isolations due to the dilution of the blood with anticoagulants.
Word   Urothelial Cancer, Urine FISH, UroVysion
Thin Prep vials for UFISH testing are available from the Molecular Pathology laboratory. Indicate the desired number of vials on a courier supply request form.
Word   Human Papilloma virus, High Risk Only
Effective 1/1/05, clients may choose to use the DNA with Pap option to screen their patients who are 30 years and older.
Word   HIV-1 RNA Viral Load
Effective July 29, 2005, NorDx will begin testing HIV-1 RNA Viral Load specimens in-house using the Bayer branched DNA (bDNA) methodology. This test is validated for Group M Subtypes A-G. The dynamic range of the assay is 75-500,000 copies/mL.
Word   Hereditary Hemochromatosis
Effective January 1, 2005, the volume of whole blood necessary for the performance of HHDNA testing is reduced to a minimum of 0.5 mL of whole blood in an EDTA tube. Volumes less than 0.5 mL may lead to failed isolations due to the dilution of the blood with anticoagulants.
Word   Her-2/neu gene amplification, FISH
Used as a prognostic factor in stage II, node-positive breast cancer patients. An aid to predict disease-free and overall survival of the above patients when treated with cyclophosphamide, doxorubicin and 5-fluorouracil. Breast cancer patients with a 2+ IHC Her-2/neu stain who are candidates for Herceptin treatment.
Word   HCV RNA Viral Load
Effective July 29, 2005, NorDx will begin testing HCV RNA Viral Load specimens in-house using the Bayer branched DNA (bDNA) methodology. The dynamic range of the assay is 615 to 7,690,000 IU/mL.
Word   Factor V Leiden
Effective January 1, 2005, the volume of whole blood necessary for the performance of Factor V Leiden testing is reduced to a minimum of 0.5 mL of whole blood in an EDTA tube.
Word   Cystic Fibrosis
Effective April 1, 2004, testing for Cystic Fibrosis Carrier Screening and Genotyping on blood samples will be performed at NorDx laboratory. Amniotic Fluid and Chorionic Villus testing will continue to be performed at Mayo Medical Laboratories (Test Code 9497).
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